Comprehensive Toxicology, Second Edition

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Comprehensive Toxicology, Second Edition
Publisher: Elsevier Science | pages: 6837 | 2010 | ISBN: 0080468683 | PDF | 138,4 mb

In more than a decade since the publication of the first edition of Comprehensive Toxicology, an explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. Revised and updated to reflect new advances in toxicology research and including content by some of the leading researchers in the field, the 14-volume second edition of Comprehensive Toxicology remains the premier resource for toxicologists in academia, medicine, and corporations. Rather than giving an alphabetical listing of compounds, Comprehensive Toxicology second edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology second edition is the most complete and valuable toxicology work available to researchers today.

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Immunotoxicity Testing: Methods and Protocols (Methods in Molecular Biology)

Immunotoxicity Testing: Methods and Protocols (Methods in Molecular Biology)
Publisher: Rodney R. Dietert | ISBN: 1607614006 | edition 2009 | PDF | 413 pages | 10,1 mb

Recent critical advances in the field of immunotoxicology have led to incredible contributions to basic science, including crucial improvements in human risk assessment. In Immunotoxicity Testing: Methods and Protocols, expert researchers explore these changes, providing the reader with current, lab-ready procedures, along with the corresponding background information that is necessary to identify effective testing approaches for chemicals and drugs. Among the first volumes to meld consideration of immunotoxicity testing strategies with a comprehensive presentation of detailed laboratory protocols, chapters include a description of the evolution of immunotoxicity testing, a look at the importance of immunotoxicity testing for health risk reduction, and ideas concerning the future of the field.

 

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Poisoning and Toxicology Handbook

"Poisoning and Toxicology Handbook, Fourth Edition" by Jerrold B. Leikin and Frank P. Paloucek
IH | 1384 pages | English | 2007, 4 edition | ISBN: 1420044796 | PDF | 12,2 MB

A unique reference containing detailed reviews of more than 900 drugs and poisons, the Poisoning and Toxicology Handbook, Fourth Edition provides the latest information on medicinal, biological, herbal, and non-medicinal agents, and antidotes. Increasing its depth and scope with analyses of newer drugs, chemicals, and environmental toxins, including drugs that have been recently approved by the FDA, this book is a compendium of useful resources.

The present volume provides locations and phone numbers of poison control centers throughout the country, organizations offering information on toxicology, and teratology information services. It presents diagnostic testing and analytical procedures, evaluates the effectiveness of antidotes, and features an extensive symptoms listing. The section on special topics provides detailed treatment protocols, hospital preparedness guidelines, position statements, and practice guidelines focused on the treatment of toxicities. This fourth edition keeps you up to date in one of the most exciting and expanding fields in medical science.

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Jet Fuel Toxicology

Mark L. Witten, Errol Zeiger, Glenn David Ritchie - Jet Fuel Toxicology
CRC Press | ISBN: 1420080202 | 2010-07-30 | PDF | 348 pages | 6.27 Mb

Currently serving as a resource for the National Center for Toxological Research in their work with the Gulf Coast oil spill, this book presents current research conducted primarily by the airforce on the toxic effects of JP-8 jet fuel on the pulmonary, immune, dermal, and nervous systems. In all, the book considers 13 toxicology studies of significance, the results of which are currently shaping US armed services policy. It will enable all of the hydrocarbon industry to make better choices regarding fuel handling.

Due to its widespread use, jet fuel is thought to be the largest toxicant exposure risk for U.S. Armed Services personnel. Taking a proactive approach to the potential dangers of repeated human exposure to hydrocarbon fuels, the Air Force Office of Scientific Research (AFOSR) sponsored a number of research projects during the last 20 years investigating health effects resulting from specific exposure to JP-8 (Jet Propellant-8).

Jet Fuel Toxicology summarizes the newest and most important results of these extensive research programs carried out by hydrocarbon fuel research groups throughout the U.S. Each book chapter highlights one specific research area from the many topical areas comprising jet fuel toxicology. After examining the contents and general action of JP-8, the book looks at how the fuel affects various body functions highlighted by:

- Effects on daily inhalation on the respiratory system
- Acute and long-term neurotoxicological and neurobehavioral effects
- Both local and systemic toxicity following exposure through the skin
- Immunotoxicity from pulmonary and dermal exposures
- Genetic damage, as evidenced in studies of the blood and bone marrow of mice

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Principles of Toxicology Testing

Frank A. Barile "Principles of Toxicology Testing"
CRC | English | 2007-07-23 | ISBN: 0849390257 | 336 pages | PDF | 6,8 MB

Principles of Toxicology Testing juxtaposes the principles of animal toxicology testing with in vitro alternative methods to highlight the importance of both fields for interpretation of the significance and relevance of the other. Beginning with the fundamentals of toxicology, the book details in vivo testing in animals and describes acute, subchronic, and chronic studies as well as toxicology testing for mutagenicity and carcinogenicity. Presenting the advantages and disadvantages of each method, it introduces in vitro alternative testing such as cellular methods for acute systemic toxicity, target organ, and local toxicity. The author considers contemporary issues such as chemical exposure, high throughput screening, and the standardization and validation of in vitro techniques.

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Preclinical Development Handbook: Toxicology

 

Preclinical Development Handbook: Toxicology by Shayne Cox Gad
Series: Pharmaceutical Development Series | Publisher: Wiley-Interscience 2008 | ISBN: 0470248467 | 1060 Pages | PDF | 7.9 MB

This book gives the professional pharmaceutical scientist a basic and comprehensive tool to facilitate the preclinical development process by bringing together, in one resource an overview of the preclinical process along with a compendium of methods and techniques that need to be considered when developing a new drug. The book details steps in the preclinical process including: prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. It includes problems that are encountered, solutions to these problems, and limitations of various methods and techniques used in determining the safety and efficacy of a drug at this stage.

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Color Atlas of Human Poisoning and Envenoming

 

Product Details

• Hardcover: 560 pages
• Publisher: Informa Healthcare; 1 edition (November 29, 2006)
• Language: English
• ISBN-10: 0849322154
• ISBN-13: 978-0849322150

Product Description

The Color Atlas of Human Poisoning and Envenoming is the only full-color resource available for the immediate visual association and the rapid identification of envenoming species, resultant lesions, clinical outcomes of envenoming or poisoning, and recommended treatment strategies to limit toxic exposures and injuries. With no-nonsense, bulleted text, tables, figure legends, and diagrams, this atlas provides an immediate reference for use in emergency differential diagnosis.

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Goldfrank's Toxicologic Emergencies (Toxicologic Emergencies)

 

Product Details

• Hardcover: 2014 pages
• Publisher: McGraw-Hill Professional; 8th edition (March 28, 2006)
• Language: English
• ISBN-10: 0071437630
• ISBN-13: 978-0071437639

Product Description

Authoritative, Up-to-Date Coverage of Every Aspect of Poison Management
A Doody's Core Title ESSENTIAL PURCHASE!
4 STAR DOODY'S REVIEW!
"...the definitive reference for the field of toxicology. This update comes four years after the seventh edition and it retains much that has made this an authoritative textbook, adds 30 new chapters, and a "new to this edition" online link to color photographs....the breadth of Goldfrank's new edition makes it worth purchasing for anyone who frequently, or even occasionally, treats toxicologic cases, even for those who own earlier editions. The editors and authors are to be commended for their compulsive revision, with attention to detail, every four years of this authoritative book."--Doody's Review Service
The #1 reference in the field for the last quarter of a century, Goldfrank's Toxicologic Emergencies, Eighth Edition, has been completely updated to equip emergency physicians with today's most authoritative guide to clinical toxicology. The book presents unsurpassed coverage of all aspects of toxicologic emergencies--from pharmacology and clinical presentation to treatment guidelines and case studies. Using a unique case-study approach, it fully examines general principles and techniques, the biochemical and molecular basis of toxicology, and how toxins affect vital signs, organs, and systems throughout the body.
The completely updated Eighth Edition features:

A case-based approach that maximizes understanding of clinical applications of the material

Easy-to-find, detailed guidance on the use of antidotes

Quick-reference tables on inside covers, providing immediate access to “must-have” vital-sign statistics, lab values, and common equations

Expanded coverage of bioterrorism, inhalant abuse, and international considerations

A companion website with more than 1200 self-assessment questions and annotated answers, critical cases in medical toxicology, and more than 100 color photos of plants, mushrooms, spiders, snakes, marine life, and dermatologic reactions of toxicologic importance

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Toxicology: A Case-Oriented Approach

 

Product Details

• Hardcover: 600 pages
• Publisher: Informa Healthcare; 1 edition (October 10, 2001)
• Language: English
• ISBN-10: 0849303710
• ISBN-13: 978-0849303715

Product Description

REAL-LIFE CASES, TUTORIAL QUESTIONS, NARRATIVE HISTORYIntriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduate combined toxicology course at West Chester University, this innovative text captures readers' interest by combining modern case studies, historical cases, and hundreds of illustrations and tables. Each chapter presents several case scenarios that involve the reader with questions about diagnosis, testing methods, treatment, and other pertinent information. TOXICOLOGY FOR THE LABORATORY AND THE EMERGENCY ROOMIn an easy-to-read style, this book covers the major organ systems and reviews the effects of toxins in each system. Most contemporary books are almost entirely clinical or entirely analytical. Toxicology: A Case-Oriented Approach treats each area extensively to benefit students and professionals who need to know aspects of both. It describes diagnosis and treatment of each specific poisonous exposure and discusses chemical basis and the laboratory testing of toxins. This dual perspective, coupled with the book's interesting narrative approach, lets readers quickly absorb the information they need to understand toxicology in the laboratory and in the Emergency Department.

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