The Skeleton: Biochemical, Genetic, and Molecular Interactions in Development and Homeostasis
Publisher: Humana Pr | ISBN: 159259736X | edition 204 | PDF | 447 pages | 11,9 mb
Publisher: Humana Pr | ISBN: 159259736X | edition 204 | PDF | 447 pages | 11,9 mb
The skeleton is a complex multifunctional system. In addition to its mechanical/structural support function, it contains the marrow in which blood cells are made and, therefore, is a critical part of the circulatory and immune systems. Also, in that it is the major reservoir for the essential element calcium, a critical component of intracellular signaling pathways, the skeleton is an integral component of the endocrine system. Furthermore, the skeleton is a dynamic system that is subject to modification (remodeling) throughout life under the influence of both intrinsic (chemical) signals and extrinsic (mechanical) signals

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